What are the pharmaceutical applications of suspension

The suspension dosage form has long been used for insoluble and poorly soluble drugs for making oral, topical and parenteral products. Pharmaceutical Suspensions, From Formulation Development to Manufacturing provides the reader with a broad overview of suspension drug product technology.

What are the different types of suspension in pharmacy?

Based on the route of administration, suspensions can be classified as oral, topical, ophthalmic, otic, or nasal suspensions. Each of these present unique challenges and requirements in terms of desired quality attributes.

What is an example of a suspension medication?

Examples of a few of the oral suspensions in which a specific and well defined particle size specification for the drug substance is important include phenytoin suspension, carbamazepine suspension, trimethoprim and sulfamethoxazole suspension, and hydrocortisone suspension.

What are suspension medications?

| In an elixir, the active ingredients are mixed with a liquid, usually a kind of syrup or alcohol, in which they can dissolve. In a suspension, the medicine is mixed with a liquid, usually water, in which it cannot dissolve and therefore remains intact in the form of small particles.

What is suspending agent in pharmaceutical?

(Pharmaceutical: Ingredients) A suspending agent is a liquid in which a solid substance can be held in suspension. The drug is held in the suspension by a suspending agent, and does not settle at the bottom. If the tablet is dissolved in a suspending agent, this will help suspend any insoluble components in the liquid.

What are the classification of suspension?

Answer: Suspensions are classified on the basis of the dispersed phase and the dispersion medium, where the former is essentially solid while the latter may either be a solid, a liquid, or a gas. three types: suspension mixture, colloidal mixture or solution, according to how they combine and can be separated.

What are the 4 types of suspension system?

Modern springing systems are based on four basic designs. Get to know these four spring classes: leaf springs, coil springs, torsion bars, and air springs.

Which of the following is the best example of suspension?

Examples of a suspension include the following: Whole milk, peanut butter, some salad dressings, hot chocolate, oil paint, muddy river water.

What is the use of Sucral suspension?

Sucral Suspension is used to treat stomach ulcers. Sucral Suspension covers the damaged ulcer tissue in the stomach and protects it against stomach acid or further injury. This helps ulcers heal more quickly. $also gives relief from pain and discomfort in the stomach associated with stomach ulcers.

What is the use of suspending agents in suspension?

SUSPENDING AGENTS  Suspending agents also called thickening agents are used to stabilize suspensions are hydrophilic colloid i.e. substances that spontaneously form colloidal dispersions with water because of an affinity between the dispersed particles and the dispersion medium.

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What factors affect suspension?

  1. Dispersed phase content. The content of the dispersed phase φ is the most important physical parameter that affects the viscosity of dispersions. …
  2. Particle shape. …
  3. Particle size and size distribution. …
  4. Temperature.

What is difference between emulsion and suspension?

An emulsion is similar to a suspension only in that it is a mixture of two components. … Unlike a suspension, which can consist of two components of any phase, an emulsion is a mixture of two liquids.

What are 5 examples of suspension?

  • Mud or muddy water: where soil, clay, or silt particles are suspended in water.
  • Flour suspended in water.
  • Kimchi suspended on vinegar.
  • Chalk suspended in water.
  • Sand suspended in water.

What types of suspension are most used today?

2. Independent Front Suspension. In this type of suspension, each front wheel is independently supported by a coil, torsion bar, or leaf spring. Most of the passenger cars now use the independent front suspension in which the coil spring system is the most common.

What are the two types of suspension?

There are two general classifications of suspension systems known to date; dependent and independent. A dependent suspension system connotes that there is a beam or axle that connects the left wheel to the right so they work in tandem with each other.

What are the advantages of suspensions?

  • A suspension is a dosage form that can improve the chemical stability of certain drugs. …
  • Suspension can improve the taste of various unpleasant/bitter tastes of the drug by masking them. …
  • The drug in suspension exhibits a higher rate of bioavailability than other dosage forms.

What are the characteristics of suspension?

  • A suspension is a heterogeneous mixture.
  • The size of solute particles in a suspension is quite large. …
  • The particles of a suspension can be seen easily.
  • The particles of a suspension do not pass through a filter paper. …
  • The suspension is unstable.

Why is Gelusil used?

This medication is used to treat the symptoms of too much stomach acid such as stomach upset, heartburn, and acid indigestion. It is also used to relieve symptoms of extra gas such as belching, bloating, and feelings of pressure/discomfort in the stomach/gut. Simethicone helps break up gas bubbles in the gut.

How does sucralfate suspension work?

Sucralfate works mainly in the lining of the stomach and is not highly absorbed into the body. This medicine adheres to ulcer sites and protects them from acids, enzymes, and bile salts. Sucralfate can heal an active ulcer, but it will not prevent future ulcers from occurring.

What is in sucralfate suspension?

CARAFATE Suspension for oral administration contains 1 g of sucralfate per 10 mL. CARAFATE Suspension also contains: colloidal silicon dioxide NF, FD&C Red #40, flavor, glycerin USP, methylcellulose USP, methylparaben NF, microcrystalline cellulose NF, purified water USP, simethicone USP, and sorbitol solution USP.

What is not example of suspension?

Milk is not an example of suspension as its components do not settle at the bottom of the container. Milk is an example of a colloid. Take water mixed with chalk powder in a bottle.

Is gelatin an example of suspension?

Suspended particles settle out of a suspension. Colloids contain some particles that are intermediate between those in a solution and those in a suspension. Examples include peanut butter, pudding, Jello, whipped cream, and even fog!

Is blood An example of suspension?

A suspension is a heterogeneous mixture of particles with diameters of about 1 µm (1000 nm) that are distributed throughout a second phase. Common suspensions include paint, blood, and hot chocolate, which are solid particles in a liquid, and aerosol sprays, which are liquid particles in a gas.

What is physical stability of suspension?

Physical stability of suspensions is the condition in which the particles do not aggregate and in which they remain uniformly distributed throughout the dispersion.

What is caking in suspensions?

The phenomena of caking and of flocculation in a sulfamerazine suspension system have been reported in the literature. … Caking of the sulfamerazine suspension system is seen when the particles settle to a dense sediment before bonds can be established between the closely-packed particles.

What is stability of suspension?

It is important to understand that suspensions are kinetically stable, but thermodynamically unstable, system. Physical stability is defined as the condition in which the particles remain uniformly distributed throughout the dispersion without any signs of sedimentation.

Is colloid and suspension same?

Particles in a suspension are usually more than 1,000 nm, while those in a colloid range from 1-1,000 nm. Unlike those in a suspension, particles in a colloid do not separate when sitting still. … Colloids are able to scatter light, but suspensions cannot transmit light.

Is milk a suspension?

No, milk is not a suspension. As discussed above, a suspension is a liquid with undissolved particles mixed up in it. … They just stay where they are, spread out mostly evenly through the liquid. This is why milk is a colloid and not a suspension.

Why are emulsions used in pharmaceuticals?

Emulsions are commonly used in many major chemical industries. In the pharmaceutical industry, they are used to make medicines more palatable, to improve effectiveness by controlling dosage of active ingredients, and to provide improved aesthetics for topical drugs such as ointments.

What are the three types of suspension?

There are three basic types of suspension components: linkages, springs, and shock absorbers.

What are solutions 5 examples?

S.NoTypes of SolutionExamples2Solid-liquidThe solution of sugar, salt etc in water.3Solid-gasSublimation of substances like iodine, camphor etc into the air.4Liquid-solidHydrated salts, mercury in amalgamated zinc, etc.5Liquid-liquidAlcohol in water, benzene in toluene